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ACT-451840

ACT-451840 is an orally active, potent, and low-toxicity antimalarial research compound with an artemisinin-like mechanism. It demonstrates rapid action against all asexual blood stages of both sensitive and resistant P. falciparum, showing 99.80% parasite reduction in vivo at 30 mg/kg. This profile supports its investigation for malaria drug discovery and resistance studies.

Product Specifications

CAS Number

1984890-99-4

Product Name Alternative

ACT451840

Field of Research

Infectious Disease & Virology

Purity

96.07% (May vary between batches)

Solubility

DMSO:30 mg/mL (39.95 mM)

Smiles

CC (=O) N1CCN (CC1) c1ccc (CN ([C@@H] (Cc2ccccc2) C (=O) N2CCN (Cc3ccc (cc3) C#N) CC2) C (=O) \C=C\c2ccc (cc2) C (C) (C) C) cc1

Molecular Formula

C47H54N6O3

Molecular Weight

750.97

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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