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NLRP3 IN 70

Compound 15 (NLRP3 IN 70) is a potent and selective NLRP3 inflammasome inhibitor, demonstrating an IC50 of 23 nM for IL-1β suppression in THP-1 cells. This small molecule is a valuable research tool for investigating NLRP3-driven pathologies in both cellular and animal models of inflammatory and autoimmune diseases.

Product Specifications

Field of Research

Cell Biology

Smiles

O=C (NS (=O) (N (C) C1CCN (C) CC1) =O) NC2=C3C (CCC3) =CC4=C2CCC4

Molecular Formula

C20H30N4O3S

Molecular Weight

406.54

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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