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NLRP3 IN 7n

The small molecule compound 7n is a potent and selective NLRP3 inflammasome inhibitor, active at nanomolar concentrations in vitro. It does not affect NLRC4 or AIM2 inflammasome pathways, making it a valuable tool for researching NLRP3-driven pathologies like gout, Alzheimer's disease, and type 2 diabetes in cellular and animal models.

Product Specifications

CAS Number

2924547-56-6

Field of Research

Cell Biology

Smiles

N (C (=O) [C@H]1N (S (=O) (=O) C2=CC=C (N) C=C2) CCCC1) C3=C4C (=CC5=C3CCC5) CCC4

Molecular Formula

C24H29N3O3S

Molecular Weight

439.57

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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