TLR8 antagonist-1
TLR8 antagonist 1 (Compound 10) is a selective small molecule inhibitor that blocks TLR8-mediated signaling by reducing MyD88 recruitment, thereby suppressing downstream NF-κB and IRF activation. This compound serves as a valuable research tool for studying TLR8-driven inflammatory responses in both cellular and animal models of autoimmune and infectious diseases.
Product Specifications
CAS Number
1111460-83-3
Field of Research
Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C (NC1CCN (CC) CC1) C2=CC=C (OCC=3C (=NOC3C) C) C (OC) =C2
Molecular Formula
C21H29N3O4
Molecular Weight
387.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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