TLR8 antagonist-1
TLR8 antagonist 1 (Compound 10) is a selective small molecule inhibitor that blocks TLR8-mediated signaling by reducing MyD88 recruitment, thereby suppressing downstream NF-κB and IRF activation. This compound serves as a valuable research tool for studying TLR8-driven inflammatory responses in both cellular and animal models of autoimmune and infectious diseases.
Product Specifications
CAS Number
1111460-83-3
Field of Research
Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C (NC1CCN (CC) CC1) C2=CC=C (OCC=3C (=NOC3C) C) C (OC) =C2
Molecular Formula
C21H29N3O4
Molecular Weight
387.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Rat Monoclonal Bim Antibody (3C5) [Alexa Fluor 488]](https://cdn.genprice.uk/genprice/uk/genprice3.webp)
NBP2-80102AF488 0.1 mL
Rat Monoclonal Bim Antibody (3C5) [Alexa Fluor 488]
Sign In for Pricing
View Details 
MBS7088915 Inquire
Recombinant Rat Mas-related G-protein coupled receptor member H (Mrgprh), partial
Sign In for Pricing
View Details 
MBS109295-01 48 Well
Qualitative Human Hepatitis B Virus Pre-S2 Antigen (HBVPS2Ag) ELISA Kit
Sign In for Pricing
View Details MBS109295-02 96 Well
Qualitative Human Hepatitis B Virus Pre-S2 Antigen (HBVPS2Ag) ELISA Kit
Sign In for Pricing
View Details