JRD-SIK1/2i-4
JRD-SIK1/2i-4 is a potent and selective small-molecule inhibitor of SIK1 and SIK2, promoting CRTC3 nuclear translocation at low μM concentrations. It is a valuable research tool for studying cAMP/CREB signaling pathways in both cellular and animal models of metabolism and inflammation.
Product Specifications
CAS Number
2810810-00-3
Field of Research
Cell Biology, Immunology & Inflammation, Signal Transduction
Smiles
N#CC=1N=CC (OC2CN (C) C2) =C (C1) C=3C=CN4N=C (C=C4C3) NC (=O) C5CC5
Molecular Formula
C21H20N6O2
Molecular Weight
388.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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