STING IN 42
STING-IN-42 is a potent and orally active small molecule inhibitor of STING palmitoylation and signaling. It effectively suppresses STING-driven inflammation in vivo, as demonstrated in CMA-challenged and Trex1-/- mouse models, making it a valuable research tool for studying cGAS-STING pathway biology in autoimmune and inflammatory diseases.
Product Specifications
CAS Number
2925028-24-4
Field of Research
Cell Biology
Smiles
O=C (NC1=CC=C (C=C1) N2CCC (F) (F) CC2) NC3=CNC=4C=CC (Cl) =CC43
Molecular Formula
C20H19ClF2N4O
Molecular Weight
404.84
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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