18-Methoxycoronaridine
18-Methoxycoronaridine is a selective α3β4 nicotinic acetylcholine receptor antagonist. It is used in research to study addiction mechanisms, as it attenuates behavioral sensitization to nicotine and reduces reward-related behaviors for substances like sucrose in vivo. Its action in the habenula-interpeduncular circuit makes it a tool for investigating reward pathways and obesity.
Product Specifications
CAS Number
308123-60-6
Smiles
C (OC) (=O) [C@]12[C@]3 ([N@] (CC (C1) (C[C@@H]3CCOC) [H]) CCC4=C2NC=5C4=CC=CC5) [H]
Molecular Formula
C22H28N2O3
Molecular Weight
368.477
Storage Conditions
-20°C
Notes
For research use only.
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