Darinaparsin
Darinaparsin is a cytotoxic dimethylarsenic-glutathione compound effective against various prostate cancer and lymphoma cell lines in vitro, with IC50 values in the low micromolar range. It modulates Hedgehog signaling and ERK phosphorylation, reduces tumor-initiating cells, and demonstrates in vivo efficacy by inhibiting tumor growth in prostate cancer xenograft models.
Product Specifications
CAS Number
69819-86-9
Field of Research
Cell Biology
Smiles
[C@@H] (NC (CC[C@@H] (C (O) =O) N) =O) (C (NCC (O) =O) =O) CS[As] (C) C
Molecular Formula
C12H22AsN3O6S
Molecular Weight
411.31
Storage Conditions
-20°C
Notes
For research use only.
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