(±) -Nornicotine (Standard)
(±) -Nornicotine (Standard) is the analytical standard of (±) -Nornicotine. This product is intended for research and analytical applications. (±) -Nornicotine is a major metabolite of Nicotine. (±) -Nornicotine is a partial nAChRs agonist, specifically activating receptor subtypes containing α7 and α6 subunits. (±) -Nornicotine disrupts β-catenin and ZO-1, and induces F-actin depolymerization. (±) -Nornicotine supports self-administration behavior. (±) -Nornicotine can be used in the research of atherosclerosis, Alzheimer's disease, and schizophrenia[1][2][3][4].
Product Specifications
CAS Number
5746-86-1
Product Name Alternative
Nornicotine (Standard)
UNSPSC
12352005
Target
Drug Metabolite; Endogenous Metabolite; nAChR; Reference Standards; β-catenin
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others; Stem Cell/Wnt
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/racemic-nornicotine-standard.html
Smiles
C1(C2CCCN2)=CN=CC=C1
Molecular Formula
C9H12N2
Molecular Weight
148.21
References & Citations
[1]Najme R, et al. Identification and characterization of Nornicotine degrading strain Arthrobacter sp. NOR5. Sci Total Environ. 2021;764:142894.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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