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FMF-04-159-2

FMF-04-159-2 is a covalent CDK14 inhibitor (IC50=39.6 nM) that reduces α-synuclein aggregation in neuronal models of Parkinson's disease and suppresses triple-negative breast cancer progression in vitro and in vivo by inhibiting Wnt/β-catenin signaling.

Product Specifications

CAS Number

2364489-81-4

Product Name Alternative

FMF 04 159 2, FMF041592, FMF-04-159-2, CDK2, CDK14/Cyclin Y

Field of Research

Cell Biology, Immunology & Inflammation, Signal Transduction, Stem Cell & Developmental Biology

Purity

96.57% (May vary between batches)

Solubility

DMSO:200 mg/mL (292.82 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (7.32 mM)

Smiles

N (C (=O) C1=C (Cl) C=C (Cl) C=C1Cl) C=2C (C (NC3CCN (S (=O) (=O) C4=CC (NC (/C=C/CN (C) C) =O) =CC=C4) CC3) =O) =NNC2

Molecular Formula

C28H30Cl3N7O5S

Molecular Weight

683.01

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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