FMF-04-159-2
FMF-04-159-2 is a covalent CDK14 inhibitor (IC50=39.6 nM) that reduces α-synuclein aggregation in neuronal models of Parkinson's disease and suppresses triple-negative breast cancer progression in vitro and in vivo by inhibiting Wnt/β-catenin signaling.
Product Specifications
CAS Number
2364489-81-4
Product Name Alternative
FMF 04 159 2, FMF041592, FMF-04-159-2, CDK2, CDK14/Cyclin Y
Field of Research
Cell Biology, Immunology & Inflammation, Signal Transduction, Stem Cell & Developmental Biology
Purity
96.57% (May vary between batches)
Solubility
DMSO:200 mg/mL (292.82 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (7.32 mM)
Smiles
N (C (=O) C1=C (Cl) C=C (Cl) C=C1Cl) C=2C (C (NC3CCN (S (=O) (=O) C4=CC (NC (/C=C/CN (C) C) =O) =CC=C4) CC3) =O) =NNC2
Molecular Formula
C28H30Cl3N7O5S
Molecular Weight
683.01
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog