FPA-124
FPA-124 is a potent, cell-permeable copper complex that selectively inhibits Akt by targeting its PH and kinase domains, inducing apoptosis. It demonstrates dose-dependent anti-proliferative effects in various cancer cell lines in vitro and has shown efficacy in xenograft tumor models in vivo, supporting its use in oncology and signal transduction research.
Product Specifications
CAS Number
902779-59-3
Product Name Alternative
FPA 124, FPA124, FPA-124, Akt Inhibitor XI
Field of Research
Cell Biology, Signal Transduction
Purity
95.04% (May vary between batches)
Solubility
H2O:< 0.1 mg/mL (insoluble) ; DMSO:2 mg/mL (5.24 mM)
Smiles
O=C1C=2C (OC=C1C=[N]3[Cu+2] ([Cl-]) ([Cl-]) [S]=C (N) N3) =CC=CC2
Molecular Formula
C11H9Cl2CuN3O2S
Molecular Weight
381.73
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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