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FPA-124

FPA-124 is a potent, cell-permeable copper complex that selectively inhibits Akt by targeting its PH and kinase domains, inducing apoptosis. It demonstrates dose-dependent anti-proliferative effects in various cancer cell lines in vitro and has shown efficacy in xenograft tumor models in vivo, supporting its use in oncology and signal transduction research.

Product Specifications

CAS Number

902779-59-3

Product Name Alternative

FPA 124, FPA124, FPA-124, Akt Inhibitor XI

Field of Research

Cell Biology, Signal Transduction

Purity

95.04% (May vary between batches)

Solubility

H2O:< 0.1 mg/mL (insoluble) ; DMSO:2 mg/mL (5.24 mM)

Smiles

O=C1C=2C (OC=C1C=[N]3[Cu+2] ([Cl-]) ([Cl-]) [S]=C (N) N3) =CC=CC2

Molecular Formula

C11H9Cl2CuN3O2S

Molecular Weight

381.73

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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