M-PEG12-NHS ester
M-PEG12-NHS ester is a heterobifunctional PROTAC linker featuring a polyethylene glycol (PEG) spacer and an amine-reactive N-hydroxysuccinimide (NHS) ester terminus. It is widely used in chemical biology for constructing PROTAC degraders, facilitating the conjugation of E3 ligase ligands to target protein binders for both in vitro and in vivo degradation studies.
Product Specifications
CAS Number
2207596-93-6
Product Name Alternative
M-PEG-12-NHS ester
Field of Research
Pharmacology & Drug Discovery
Solubility
DMSO:100 mg/mL (145.82 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (5.83 mM)
Smiles
O=C (ON1C (=O) CCC1=O) CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC
Molecular Formula
C30H55NO16
Molecular Weight
685.76
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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