YHS-12
YHS-12 is an ionizable cationic lipid (pKa 6.506) used to formulate macrophage-targeted LNPs for co-delivery of mRNA and siRNA. These LNPs enhance anti-MRSA phagocytosis in vitro in RAW 264.7 and BMDM cells and improve survival in murine sepsis models, demonstrating utility in immunotherapy and infectious disease research.
Product Specifications
CAS Number
2959463-68-2
Smiles
N (CCNC (/C=C/C (NCCN (CCCCCCCCCCCC) CCCCCCCCCCCC) =O) =O) (CCCCCCCCCCCC) CCCCCCCCCCCC
Molecular Formula
C56H112N4O2
Molecular Weight
873.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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