6,6′-Trehalose Dioleate
6,6′-Trehalose dioleate (6,6′-TDO) is a glycolipid excipient for mRNA encapsulation in lipid nanoparticles (LNPs), enhancing immunogenicity in vaccine research. In vivo studies show it promotes a Th1/Th2 antibody response (IgG2a/IgG1) without inducing significant hepatotoxicity or renal markers in mice, supporting its use for safer nucleic acid delivery platforms.
Product Specifications
CAS Number
338733-40-7
Smiles
O ([C@H]1O[C@H] (COC (CCCCCCC/C=C\CCCCCCCC) =O) [C@@H] (O) [C@H] (O) [C@H]1O) [C@H]2O[C@H] (COC (CCCCCCC/C=C\CCCCCCCC) =O) [C@@H] (O) [C@H] (O) [C@H]2O
Molecular Formula
C48H86O13
Molecular Weight
871.19
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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