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6,6′-Trehalose Dioleate

6,6′-Trehalose dioleate (6,6′-TDO) is a glycolipid excipient for mRNA encapsulation in lipid nanoparticles (LNPs), enhancing immunogenicity in vaccine research. In vivo studies show it promotes a Th1/Th2 antibody response (IgG2a/IgG1) without inducing significant hepatotoxicity or renal markers in mice, supporting its use for safer nucleic acid delivery platforms.

Product Specifications

CAS Number

338733-40-7

Smiles

O ([C@H]1O[C@H] (COC (CCCCCCC/C=C\CCCCCCCC) =O) [C@@H] (O) [C@H] (O) [C@H]1O) [C@H]2O[C@H] (COC (CCCCCCC/C=C\CCCCCCCC) =O) [C@@H] (O) [C@H] (O) [C@H]2O

Molecular Formula

C48H86O13

Molecular Weight

871.19

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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