STAT3-IN-14
STAT3-IN-14 (Compound 1) is a STAT3 inhibitor and has STAT3 phosphorylation inhibitory activity. STAT3-IN-14 (Compound 1) can directly bind to the hinge region of STAT3[1].
Product Specifications
CAS Number
[123297-90-5]
UNSPSC
12352005
Target
STAT
Type
Natural Products
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/stat3-in-14.html
Purity
95.89
Solubility
DMSO : 120 mg/mL (ultrasonic)
Smiles
O=C(C1=C2OC([C@@H](O)C)=C1)C3=C(C2=O)C=CC=C3O
Molecular Formula
C14H10O5
Molecular Weight
258.23
References & Citations
[1]Teruyuki Tahara, et al. STAT3 inhibitory activity of naphthoquinones isolated from Tabebuia avellanedae. Bioorg Med Chem. 2020 Mar 15;28 (6) :115347.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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