Lathosterol-d7

Lathosterol-d7 is deuterium labeled Lathosterol (HY-113486) . Lathosterol is a plant sterol and cholesterol-like molecule. Lathosterol increases antioxidant enzymes (such as SOD, CAT, and GSH) and decreases LDH. Lathosterol has a hepatoprotective effect on mice with acetaminophen (HY-66005) -induced liver injury[1][2].

Product Specifications

CAS Number

[2260669-10-9]

UNSPSC

12352211

Target

Endogenous Metabolite; Isotope-Labeled Compounds; Lactate Dehydrogenase; SOD

Type

Isotope-Labeled Compounds

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Solubility

10 mM in DMSO

Smiles

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])([H])C3=CC[C@](C[C@H](CC4)O)([H])[C@@]4(C)[C@@]3([H])CC1

Molecular Formula

C27H39D7O

Molecular Weight

393.70

References & Citations

[1]Kempen HJ, et al. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis in humans. J Lipid Res. 1988 Sep;29 (9) :1149-55.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-223.