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AZASPIRENE

Azaspirene is a novel 1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione-based angiogenesis inhibitor. It suppresses VEGF-induced HUVEC migration in vitro and its analogs show potential antitumor activity against uterine adenocarcinoma, likely via anti-angiogenic mechanisms in vivo.

Product Specifications

CAS Number

461644-34-8

Field of Research

Cardiovascular Research, Signal Transduction

Smiles

O[C@@H]1[C@@]2 (OC (/C=C/C=C/CC) =C (C) C2=O) C (=O) N[C@]1 (CC3=CC=CC=C3) O

Molecular Formula

C21H23NO5

Molecular Weight

369.41

Storage Conditions

-20°C

Notes

For research use only.

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