AZD5991 sodium
AZD5991 is a macrocyclic, sub-nanomolar Mcl-1 inhibitor that disrupts Mcl-1's interaction with pro-apoptotic proteins, inducing apoptosis. It demonstrates potent anti-tumor activity in hematological cancer models, supporting its use in both in vitro mechanistic studies and in vivo efficacy research.
Product Specifications
CAS Number
2143061-85-0
Smiles
O=C (C1=C2C3=C (N1C) C (C4=C (C) N (C) N=C4CSCC5=NN (C) C (CSC6=CC7=C (C=CC=C7) C (OCCC2) =C6) =C5) =C (Cl) C=C3) [O-].[Na+]
Molecular Formula
C35H33ClN5NaO3S2
Molecular Weight
694.24
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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