M4K2281
M4K2281 is a potent and selective ALK2 inhibitor with a biochemical IC50 of 2 nM, demonstrating efficacy in cellular assays. Its moderate-to-high brain-to-plasma ratio supports its utility in researching ALK2-related pathologies, including fibrodysplasia ossificans progressiva (FOP), in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
3034840-19-9
Smiles
N1=CC (C2=CC (OC) =C (OC) C (OC) =C2) =C3C (=C1) C4=CC=C (C=C4OCC3) N5CCN (C) CC5
Molecular Formula
C27H31N3O4
Molecular Weight
461.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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