PF-07265028
PF-07265028 is a potent and selective HPK1 inhibitor (IC50 = 17 nM) that blocks its kinase activity to relieve immune suppression. This action enhances T-cell function and has shown potential in preclinical models to remodel the tumor microenvironment and promote anti-tumor immunity, supporting its investigation in immuno-oncology research.
Product Specifications
CAS Number
2736458-30-1
Field of Research
Signal Transduction
Purity
99.45% (May vary between batches)
Smiles
[C@H] (CC) (N) C1=C2C (C (=O) N (C2) C=3N=C (C=CC3) C=4N5C (=NN4) CC[C@@H]5C) =CC (=N1) N6[C@H] (C) CCC6
Molecular Formula
C26H32N8O
Molecular Weight
472.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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