Imarikiren
TAK-272 (Imarikiren) is a potent, selective, and orally active direct renin inhibitor for research. It shows strong in vitro activity against human renin (IC50 = 2.1 nM) and demonstrates dose-dependent, sustained antihypertensive effects in rat models, supporting its investigation for diabetic nephropathy.
Product Specifications
CAS Number
1202265-63-1
Smiles
C (CCCOC) N1C (C (N (CC (C) C) [C@H]2C[C@@H] (C (=O) N3CCOCC3) CNC2) =O) =NC=4C1=CC=CC4
Molecular Formula
C27H41N5O4
Molecular Weight
499.65
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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