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Simufilamum Dihydrochloride Monohydrate

Simufilam (PTI-125) is an oral small molecule that selectively binds and reverses pathogenic conformations of filamin A in Alzheimer's disease. It reduces key AD pathologies, including Aβ42 aggregation and tau hyperphosphorylation, with efficacy demonstrated from picomolar concentrations in vitro using post-mortem AD brain tissue.

Product Specifications

CAS Number

2375909-85-4

Smiles

O=C1N (C2 (CCN (CC2) C) NC1) CC3=CC=CC=C3.Cl.Cl.O

Molecular Formula

C15H25Cl2N3O2

Molecular Weight

350.28

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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