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Pixatimod

Pixatimod (PG-545) is a synthetic heparan sulfate mimetic and TLR9 agonist with demonstrated immunostimulatory, antitumor, and antiviral activity. It inhibits SARS-CoV-2 entry and suppresses tumor progression in numerous preclinical in vivo models, showing combinatory potential with various chemotherapies and immunotherapies.

Product Specifications

CAS Number

1144617-49-1

Field of Research

Immunology & Inflammation, Infectious Disease & Virology

Smiles

C[C@@]12[C@@]3 ([C@] ([C@]4 ([C@] (C) (CC3) [C@@] ([C@@H] (CCCC (C) C) C) (CC4) [H]) [H]) (CC[C@]1 (C[C@@H] (O[C@H]5[C@H] (OS (=O) (=O) O) [C@@H] (OS (=O) (=O) O) [C@H] (O[C@@H]6[C@H] (OS (=O) (=O) O) [C@@H] (OS (=O) (=O) O) [C@H] (O[C@@H]7[C@H] (OS (=O) (=O) O) [C@@H] (OS (=O) (=O) O) [C@H] (O[C@@H]8[C@H] (OS (=O) (=O) O) [C@@H] (OS (=O) (=O) O) [C@H] (OS (=O) (=O) O) [C@@H] (COS (=O) (=O) O) O8) [C@@H] (COS (=O) (=O) O) O7) [C@@H] (COS (=O) (=O) O) O6) [C@@H] (COS (=O) (=O) O) O5) CC2) [H]) [H]) [H]

Molecular Formula

C51H88O60S13

Molecular Weight

2078.05

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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