RR-49
RR-49 is a novel difluorinated analog exhibiting remarkable pH-dependent potency. It shows a 19-fold increase in potency at pH 6.5 versus pH 7.4 in MOR cAMP inhibition assays, making it a promising candidate for in vitro and in vivo research into targeted analgesics for inflammatory pain conditions.
Product Specifications
CAS Number
2376328-79-7
Smiles
O=C (N (C=1C=CC=CC1) C2CCN (CC2) CC (F) C=3C=CC=CC3F) CC
Molecular Formula
C22H26F2N2O
Molecular Weight
372.45
Storage Conditions
-20°C
Notes
For research use only.
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