SIAIS125
SIAIS125 is an irreversible covalent PROTAC degrader targeting the epidermal growth factor receptor (EGFR) . It has demonstrated potent degradation of EGFR in cellular assays and shows potential for investigating resistance mechanisms in non-small cell lung cancer research models.
Product Specifications
CAS Number
2600730-82-1
Smiles
O=C (C=C) NC1=CC=2C (=NC=NC2NC3=CC=C (F) C (Cl) =C3) C=C1OCCCN4CCN (C (=O) CCCCCNC5=CC=CC=6C (=O) N (C (=O) C56) C7C (=O) NC (=O) CC7) CC4
Molecular Formula
C43H45ClFN9O7
Molecular Weight
854.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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