(S, R, S, R) -AHPC-Me
(S, R, S, R) -AHPC-Me serves as a VHL ligand that facilitates the recruitment of the VHL protein.
Product Specifications
CAS Number
[2055344-67-5]
UNSPSC
12352005
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-r-s-r-ahpc-me.html
Smiles
CC(C)(C)[C@H](N)C(N1[C@@H](C[C@H](C1)O)C(N[C@@H](C2=CC=C(C3=C(N=CS3)C)C=C2)C)=O)=O
Molecular Formula
C23H32N4O3S
Molecular Weight
444.59
References & Citations
[1]Jiajun Dong, et al. Small Molecule Degraders of Protein Tyrosine Phosphatase 1B and T-Cell Protein Tyrosine Phosphatase for Cancer Immunotherapy. Angew Chem Int Ed Engl. 2023 May 22;62 (22) :e202303818.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Von Hippel-Lindau (VHL)
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