(S, R, S, R) -AHPC-Me

(S, R, S, R) -AHPC-Me serves as a VHL ligand that facilitates the recruitment of the VHL protein.

Product Specifications

CAS Number

[2055344-67-5]

UNSPSC

12352005

Target

Ligands for E3 Ligase

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/s-r-s-r-ahpc-me.html

Smiles

CC(C)(C)[C@H](N)C(N1[C@@H](C[C@H](C1)O)C(N[C@@H](C2=CC=C(C3=C(N=CS3)C)C=C2)C)=O)=O

Molecular Formula

C23H32N4O3S

Molecular Weight

444.59

References & Citations

[1]Jiajun Dong, et al. Small Molecule Degraders of Protein Tyrosine Phosphatase 1B and T-Cell Protein Tyrosine Phosphatase for Cancer Immunotherapy. Angew Chem Int Ed Engl. 2023 May 22;62 (22) :e202303818.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Von Hippel-Lindau (VHL)

Curated Selection

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