Lecozotan
Lecozotan (SRA-333) is a selective 5-HT1A receptor antagonist developed for Alzheimer's disease research. It enhances potassium-stimulated glutamate and acetylcholine release in the hippocampus, improving cognition in rat models without inducing tolerance or affecting anxiety. This compound is a valuable tool for in vivo and in vitro studies of cognitive function and cholinergic/glutamatergic neurotransmission.
Product Specifications
CAS Number
434283-16-6
Smiles
[C@H] (CN (C (=O) C1=CC=C (C#N) C=C1) C2=CC=CC=N2) (C) N3CCN (C4=C5C (=CC=C4) OCCO5) CC3
Molecular Formula
C28H29N5O3
Molecular Weight
483.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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