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LC-04-045

LC-04-045 is a potent and selective molecular glue degrader targeting NEK7, achieving 90% degradation at 7 nM in MOLT-4 cells via the UPS. It effectively inhibits IL-1β and IL-18 secretion, making it a valuable tool for studying NLRP3 inflammasome biology and inflammatory disease mechanisms.

Product Specifications

Field of Research

Immunology & Inflammation, Signal Transduction

Molecular Formula

C32H28ClN5O3

Molecular Weight

566.05

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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