SGK1-IN-6
SGK1-IN-6 (compound 12f) is a potent small molecule inhibitor of SGK1, demonstrating an IC50 of 0.39 μM. It has shown efficacy in inhibiting tumor growth in PC3 cell xenograft models in mice without signs of toxicity, supporting its use in cancer research and kinase signaling studies.
Product Specifications
CAS Number
3046378-98-4
Field of Research
Cell Biology, Metabolism Research
Smiles
O=C (NC1=CC=C (OC) C=C1) C2=CC=3C (=NC (=CC3C (F) (F) F) NC4=CC=C (C=C4OC) N5CCNCC5) C=C2OC
Molecular Formula
C30H30F3N5O4
Molecular Weight
581.586
Storage Conditions
-20°C
Notes
For research use only.
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