EMD-95885

EMD-95885 is a potent and selective NR2B subunit-containing NMDA receptor antagonist (IC50 = 3.9 nM) with minimal activity at other NMDA receptor sites. It is a valuable research tool for investigating the role of NR2B in neurological processes, applicable in both in vitro binding assays and in vivo models of neuropathic pain and neurodegeneration.