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MU147

MU147 is a selective MRE11 nuclease inhibitor and chemical probe that disrupts double-strand break repair and replication fork stability. It exhibits anticancer activity in vitro and in vivo, showing synthetic lethality in BRCA2-deficient cellular models, making it a valuable tool for DNA damage response research.

Product Specifications

CAS Number

2379405-61-3

Field of Research

Cell Biology

Smiles

N (C (/C (=C/C1=CC (O) =C (O) C=C1) /C#N) =O) C2=NC (=CS2) C3=CC=CC=C3

Molecular Formula

C19H13N3O3S

Molecular Weight

363.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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