MU147
MU147 is a selective MRE11 nuclease inhibitor and chemical probe that disrupts double-strand break repair and replication fork stability. It exhibits anticancer activity in vitro and in vivo, showing synthetic lethality in BRCA2-deficient cellular models, making it a valuable tool for DNA damage response research.
Product Specifications
CAS Number
2379405-61-3
Field of Research
Cell Biology
Smiles
N (C (/C (=C/C1=CC (O) =C (O) C=C1) /C#N) =O) C2=NC (=CS2) C3=CC=CC=C3
Molecular Formula
C19H13N3O3S
Molecular Weight
363.39
Storage Conditions
-20°C
Notes
For research use only.
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