ErSO-TFPy
ErSO-TFPy is a potent cytotoxic small molecule that selectively induces necrosis in ERα-positive breast cancer cells via TRPM4 channel activation, disrupting intracellular ion balance. It demonstrates low nanomolar in vitro efficacy and has shown promising antitumor activity in mouse xenograft models, supporting its use in oncology research.
Product Specifications
CAS Number
3035547-78-2
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C1[C@@] (C=2C (N1) =C (C (F) (F) F) C=CC2) (N3CC (F) (F) C (F) (F) C3) C4=CC=C (O) C=C4
Molecular Formula
C19H13F7N2O2
Molecular Weight
434.307
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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