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MU1409

MU1409 is a small molecule inhibitor of MRE11 nuclease (IC50=12.1 μM) that also suppresses FEN1 and EXO1. It disrupts DNA repair pathways and stabilizes stalled replication forks in BRCA2-deficient cells, making it a valuable research tool for studying synthetic lethality and BRCA-mutant cancer models in vitro.

Product Specifications

CAS Number

2379671-78-8

Field of Research

Cell Biology

Smiles

C (C=1N=C (NC (/C (=C/C2=CC (Br) =C (O) C (O) =C2) /C#N) =O) SC1) C3=CC=CC=C3

Molecular Formula

C20H14BrN3O3S

Molecular Weight

456.312

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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