MY-1576
MY-1576 is a potent FAK inhibitor (IC50 = 8 nM) that activates the Hippo pathway to suppress YAP/TAZ activity. It demonstrates robust anti-tumor efficacy in KYSE30 xenograft models and effectively reduces FAK autophosphorylation and YAP/TAZ levels in vivo, supporting its use in cancer research.
Product Specifications
CAS Number
3097026-24-6
Field of Research
Cardiovascular Research, Signal Transduction, Stem Cell & Developmental Biology
Smiles
CNC (C1=CC=CC=C1NC2=NC (NC3=CC=C (NC (N4CCN (CC) CC4) =O) C=C3) =NC=C2Cl) =O
Molecular Formula
C25H29ClN8O2
Molecular Weight
509.01
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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