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VU6033685

VU6033685 is an orally bioavailable mGlu1/5 positive allosteric modulator (PAM) with selectivity for mGlu1 (EC50=39 nM) . It demonstrates in vivo efficacy in rodent models of psychostimulant-induced hyperactivity and NMDA receptor antagonist-induced cognitive deficits, supporting its research use in neuropsychiatric disorders.

Product Specifications

Field of Research

Neuroscience

Molecular Formula

C20H19ClN4O

Molecular Weight

366.84

Storage Conditions

-20°C

Notes

For research use only.

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