Nur77 modulator 4

Nur77 modulator 4 (Compound 15h) is a potent small molecule inducer of Nur77 (KD = 0.477 μM) that triggers apoptosis via ER stress pathways. It demonstrates strong anti-proliferative activity in vitro against cancer cell lines like HepG2 and MCF-7 (IC50 < 5 μM), making it a valuable tool for oncology and cell death mechanism research.