JAK1/STAT3-IN-1
JAK1/STAT3-IN-1 (4f) is a small molecule inhibitor of the JAK1/STAT3 pathway, demonstrating anti-atopic dermatitis activity with an IC50 of 2.17 μM against NO production in vitro. In vivo, it alleviates AD-like skin lesions in MC903-induced mice by reducing inflammatory infiltration and downregulating p-JAK1 and p-STAT3 expression.
Product Specifications
Field of Research
Cancer Biology, Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Molecular Formula
C30H33FN4O3S
Molecular Weight
548.67
Storage Conditions
-20°C
Notes
For research use only.
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