LNK01004
LNK01004 is a potent, multi-targeted JAK inhibitor with IC50 values of 10 nM, <0.51 nM, and 1.0 nM for JAK1, JAK2, and TYK2, respectively. It effectively blocks cytokine-induced STAT phosphorylation and is a valuable research tool for studying inflammatory skin conditions like atopic dermatitis in both cellular and animal models.
Product Specifications
CAS Number
2445500-24-1
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
N#CCNC (=O) C=1C=CC (=CC1) C2=NC (=NC=C2C) NC=3C=NN (C3) C4CC (OC (C) (C) C4) (C) C
Molecular Formula
C26H31N7O2
Molecular Weight
473.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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