BuChE-IN-16

BuChE-IN-16 is a potent, selective, and brain-penetrant butyrylcholinesterase inhibitor (IC50 = 0.33 μM) . It demonstrates neuroprotective and anti-inflammatory properties, validated in vitro and in vivo by improving cognitive deficits in both zebrafish AD models and scopolamine-impaired mice, making it a valuable tool for Alzheimer's disease research.