MI-888 TFA
MI-888 (TFA) is a potent, orally bioavailable small molecule MDM2-p53 interaction inhibitor with a Ki of 0.44 nM. It demonstrates robust antitumor efficacy in preclinical studies, inducing rapid and durable tumor regression in xenograft mouse models, supporting its use in cancer research both in vitro and in vivo.
Product Specifications
CAS Number
1303609-30-4
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
C (C (O) =O) (F) (F) F.C (C (C) (C) C) [C@H]1[C@@]2 ([C@H] ([C@H] (C (N[C@H]3C[C@@] (C) (O) C3) =O) N1) C4=C (F) C (Cl) =CC=C4) C=5C (NC2=O) =CC (Cl) =CC5
Molecular Formula
C30H33Cl2F4N3O5
Molecular Weight
662.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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