MC-25B
MC-25B is a potent and selective PROTAC degrader of FKBP12, achieving 89% maximal degradation with a DC50 of 0.35 μM. Its DCAF16-dependent mechanism effectively targets nuclear FKBP12, making it a valuable chemical probe for studying FKBP12 biology in proteolysis-targeting chimera and molecular glue research, applicable in both cellular and biochemical assays.
Product Specifications
Field of Research
Cell Biology, Immunology & Inflammation
Molecular Formula
C65H92ClN7O14
Molecular Weight
1230.92
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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