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MC-25B

MC-25B is a potent and selective PROTAC degrader of FKBP12, achieving 89% maximal degradation with a DC50 of 0.35 μM. Its DCAF16-dependent mechanism effectively targets nuclear FKBP12, making it a valuable chemical probe for studying FKBP12 biology in proteolysis-targeting chimera and molecular glue research, applicable in both cellular and biochemical assays.

Product Specifications

Field of Research

Cell Biology, Immunology & Inflammation

Molecular Formula

C65H92ClN7O14

Molecular Weight

1230.92

Storage Conditions

-20°C

Notes

For research use only.

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