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PRMT5-IN-48

PRMT5-IN-48 (D3) is an orally bioavailable, potent PRMT5 inhibitor (IC50 = 20.7 nM) with demonstrated antitumor activity. It suppresses cancer cell proliferation, induces apoptosis, and causes G0/G1 phase arrest in vitro, supporting its research application in non-Hodgkin's lymphoma models.

Product Specifications

CAS Number

2640287-77-8

Field of Research

Epigenetics & Chromatin

Smiles

C ([C@@H] (CN1CC=2C (CC1) =CC=CC2) O) N3CC4 (C=5C (C3=O) =CC (NC6CC7 (C6) CN (C (C) =O) C7) =NC5) CC4

Molecular Formula

C30H37N5O3

Molecular Weight

515.646

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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