PRMT5-IN-48
PRMT5-IN-48 (D3) is an orally bioavailable, potent PRMT5 inhibitor (IC50 = 20.7 nM) with demonstrated antitumor activity. It suppresses cancer cell proliferation, induces apoptosis, and causes G0/G1 phase arrest in vitro, supporting its research application in non-Hodgkin's lymphoma models.
Product Specifications
CAS Number
2640287-77-8
Field of Research
Epigenetics & Chromatin
Smiles
C ([C@@H] (CN1CC=2C (CC1) =CC=CC2) O) N3CC4 (C=5C (C3=O) =CC (NC6CC7 (C6) CN (C (C) =O) C7) =NC5) CC4
Molecular Formula
C30H37N5O3
Molecular Weight
515.646
Storage Conditions
-20°C
Notes
For research use only.
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