FAK-IN-24
FAK-IN-24 (Compound 9f) is a highly potent FAK inhibitor (IC50 = 0.815 nM) that induces DNA damage and apoptosis. It demonstrates robust anti-proliferative activity in glioblastoma cell lines like U87-MG and U251 and suppresses tumor growth in U87-MG xenograft models, supporting its investigation in oncology research.
Product Specifications
CAS Number
3062175-62-3
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
O=C (OCCN1CCN (C2=CC=C (C=C2) NC3=NC=C (C (=N3) NC=4C=CC=CC4C (=O) NC) C (F) (F) F) CC1) CCCC5=CC=C (C=C5) N (CCCl) CCCl
Molecular Formula
C39H45Cl2F3N8O3
Molecular Weight
801.728
Storage Conditions
-20°C
Notes
For research use only.
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