BAG3/HSP70-IN-1

USP1-IN-11 is a selective, reversible, non-competitive USP1 inhibitor that activates the DNA damage response, inducing cell cycle arrest and apoptosis. It synergizes with agents like Olaparib and Andrographolide in vitro and shows dose-dependent antitumor efficacy in MDA-MB-436 xenograft models in vivo.